
About Longwood Healthcare Leaders Meeting
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The Swiss Biotech Day is the leading biotechnology conferences in Switzerland.
? Meet senior experts from the life science industry from across Europe.
? Swiss Biotech Success Stories.
? Innovative biotech start-ups and medium-sized biotech companies.
? Thematically focused panel discussions.
ʱ¼ä (Date): May 2-3, 2022
ËùÔÚ (Location): Basel, Switzerland
չλ (Booth): #13

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Medicilon VP of UK and Europe Business Development Ms. Nadine Su in person and Medicilon Executive VP and Head of IDSU, Dr. Xuedong Dai online, are invited to give a presentation to introduce Medicilon fully integrated drug discovery platform and focus on the topic of ¡°PROTACs: Make Undruggable Targets Druggable¡±.
About Presenter
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Dr. Xuedong Dai
Executive VP and Head of IDSU (International Discovery Service Unit) at Medicilon, obtained his Ph.D. in organic chemistry at MIT. He is a senior-level expert with over 20 years of experience focusing on small molecule drug discovery and development in CNS, infectious disease, and oncology therapy areas. He has deep understanding and practical knowledge of drug discovery process, including lead identification, optimization, and development of high quality clinical candidate molecules. Prior to Medicilon, Dr. Dai worked at Janssen, HD Biosciences, GSK, and Xenoport with a demonstrated successful track record of program leadership and made significant contributions to medicinal chemistry programs that led to the marketed drug Horizant?/Regnite? and several other clinical candidates (JNJ-75276617, arbaclofen placarbil, XP21279, and XP23829).
Ms. Nadine Su
20 years¡¯ experience of project management and business development in pharmaceutical and healthcare industries include different sectors, include novel drug research and development, biotechnology application research project management, licensing and new business development in pharmaceutical and healthcare industry in Europe and China. She successfully developed and established the research partnership and business collaboration between EU and China for different novel drug research, novel biotechnology collaboration to achieve over $20M of licensing projects in a year.
Medicilon International Discovery Service Unit
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The mission of Medicilon International Discovery Service Unit is to provide high quality, efficient and cost-effective synthetic chemistry, drug design, and new drug candidate compound services to global pharmaceutical companies. We are stride to meet the research and development needs of the clients in various chemical fields of pre-clinical new drug research, shorten the cycle of drug R&D, and reduce the cost of drug R&D.
Medicilon International Discovery Service Unit has a management team and lab personnel with a rich background of studying abroad, a world-leading synthesis and analysis laboratory with installed state-of-the-art instruments and equipment. In order to provide clients with better services, the International Discovery Service Unit keeps up with new developments and new technologies in drug design and synthesis, such as artificial intelligence/machine learning (AI/ML), proteolysis targeting chimera (PROTAC), antibody-drug conjugates (ADC), direct functionalization of inert carbon-hydrogen bonds, photoredox reactions, and flow chemistry, etc.
Medicilon PROTAC Platform
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PROTACÒ©Îï·¢Ã÷ÊÖÒÕÆ½Ì¨»ã×ÜÁËÄ¿½ñÊ¢ÐеÄÈÈÃŵİбêÂѰ×ÅäÌ壻½¨ÉèÁËÆÕ±éµÄÈÈÃŰÐÏòÂѰ׸߶ÈÇ׺ÍÁ¦Ð¡·Ö×Ó¼°Ð¡·Ö×ÓÆ¬¶Ï»¯ºÏÎï¿â£¨TPSM£©£¬ÆÕ±éµÄE3ÅþÁ¬Ã¸£¬¸ß¶ÈÇ׺ÍÁ¦µÄС·Ö×Ó¼°Ð¡·Ö×ÓÆ¬¶Ï£¨E3SM£©£»½¨ÉèÁËlinkerϵͳ,°üÀ¨ÍøÂç´ó×Ú¾ßÓÐÆÕ±é¶àÑùÐÔµÄË«¹ÙÄÜÍÅÅþÁ¬Ì壨BF-Linker£©¡£ÕâЩ»ýÀ۵ϝºÏÎï¿â¿ÉÒÔ×ÊÖú¿ìËÙ¸ßЧµÄºÏ³É´ó×ڸ߻îÐÔPROTACË«ÌØÒìÐÔС·Ö×Ó£¬¼«´óµØÌá¸ß½ÓÄÉPROTACÊÖÒÕ¾ÙÐеÄÒ©ÎïÑз¢Àú³Ì¡£³ýÁË¿ìËٺϳÉÖ®Í⣬ÎÒÃÇͬʱ½¨ÉèºÍÍêÉÆµÄPROTACÉúÎïɸѡÓë²âÊÔÆ½Ì¨£¬ºóÐøÉú³¤¹âÁÙ´²Ç°ËùÓн׶Ρ£
Medicilon¡¯s PROTAC drug discovery technology platform covers the currently popular target protein ligands. Medicilon has established a linker system with an extensive collection of bifunctional linkers. Together with our expanding E3 ubiquitin ligase binder library, Medicilon can efficiently synthesize a substantial amount of highly active PROTAC bispecific small molecules, which would have the potential to significantly facilitate ithe drug discovery and development process. In addition, Medicilon has established as well as improved the PROTAC biological screening and testing platform throughout the pre-clinical stages.
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